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Analysis of institutional authors

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February 27, 2026
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Article

Phenolic compounds and multifunctional properties of thinned apples: revalorizing fruit by-products for industrial applications

Publicated to: Food Chemistry: X. 34 103640- - 2026-02-01 34(), DOI: 10.1016/j.fochx.2026.103640

Authors:

Cano-Lou, Javier; Casado-Hidalgo, Gema; Les, Francisco; Pina, Ana; Acquaticci, Laura; Caprioli, Giovanni; Lopez, Victor
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Affiliations

Ctr Invest & Tecnol Agroalimentaria Aragon CITA, Unidad Hortofruticultura, Av Montanana 930, Zaragoza 50059, Spain - Author
Univ Camerino, Sch Pharm, Chem Interdisciplinary Project CHIP, Via Madonna Carceri, I-62032 Camerino, Italy - Author
Univ San Jorge, Fac Hlth Sci, Dept Pharm, Zaragoza 50830, Spain - Author
Zaragoza Univ, Inst Agrifood Res Aragon, CITA, IA2, Zaragoza 50013, Spain - Author
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Abstract

Thinned apples are a common by-product of apple orchards, produced in abundant quantities through thinning or natural drop, leading to the loss of substantial amounts of phenolic compounds with potential bioactive properties. Ten thinned apple samples, representing both commercial and autochthonous cultivars, were ultrasonicated using ethanol as green solvent, with the main goal of reusing their phenolic content for industrial and nutritional applications. For this reason, the phenolic content was characterized with high-performance liquid chromatography coupled with tandem mass spectrometry (HPLC-MS/MS). The antioxidant, antidiabetic, and cardiovascular activities were evaluated and correlated with the targeted phenolic compounds. Under noncytotoxic conditions in Caco-2, HepG2 and HFF-1 cells, Amarilla de Octubre and Pomera de Pomes Agrias showed the strongest antioxidant-antiglycation activity as well as ACE inhibition, while Reineta and Verde Doncella excelled in HMGR and ACE inhibition. Pomera de Pomes Agrias, Vadiello-02, Reineta and Verde Doncella led digestive enzymes under Caco-2 safety.
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Keywords

ExtracciónMalusManzanaPolifenolesPropiedades antioxidantesSubproductos

Quality index

Bibliometric impact. Analysis of the contribution and dissemination channel

The work has been published in the journal Food Chemistry: X due to its progression and the good impact it has achieved in recent years, according to the agency WoS (JCR), it has become a reference in its field. In the year of publication of the work, 2026, it was in position 11/182, thus managing to position itself as a Q1 (Primer Cuartil), in the category Food Science & Technology.

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Impact and social visibility

From the perspective of influence or social adoption, and based on metrics associated with mentions and interactions provided by agencies specializing in calculating the so-called "Alternative or Social Metrics," we can highlight as of 2026-03-12:

With a more dissemination-oriented intent and targeting more general audiences, we can observe other more global scores such as:

    It is essential to present evidence supporting full alignment with institutional principles and guidelines on Open Science and the Conservation and Dissemination of Intellectual Heritage. A clear example of this is:

    • The work has been submitted to a journal whose editorial policy allows open Open Access publication.
    • Assignment of a Handle/URN as an identifier within the deposit in the Institutional Repository: http://hdl.handle.net/10532/8141
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    Leadership analysis of institutional authors

    This work has been carried out with international collaboration, specifically with researchers from: Italy.

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    Awards linked to the item

    This work is part of the APPLEDIV Project (Multidisciplinary approach for exploiting genetic diversity to increase the value of autochthonous apple: valorizing local apple by-products and wastes through bioactive compounds PID2022-141847OR-C33) funded by the Research State Agency in the 2022 call for Projects of Generation Knowledge oriented towards societal challenges.
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