Intercropping medicinal and aromatic plants with other crops has demonstrated substantial potential for improving sustainable agricultural systems. Across a wide range of species, including yarrow, dill, wormwood, pot marigold, ajowan, coriander, saffron, cumin, lemongrass, Moldavian dragonhead, fennel, hyssop, dragons head, lavender, chamomile, lemon balm, mint, black cumin, basil, rose-scented geranium, aniseed, patchouli, rosemary, sage, summer savory, marigold, thyme, fenugreek, and vetiver, integration with cereals, legumes, vegetables, and perennial trees enhanced both land use efficiency and overall crop productivity. These systems often resulted in improved essential oil (EO) yield and composition, optimized plant growth, and increased economic returns, particularly when combined with organic inputs or biofertilizers. In addition to productivity gains, intercropping provides important ecological benefits. It can enhance soil fertility, stimulate microbial activity, and contribute to effective pest and weed management. Incorporating medicinal and aromatic plants into orchards, vineyards, or agroforestry systems further supported biodiversity. It influenced secondary metabolite production in companion crops, demonstrating the multifunctional role of these species in integrated farming systems. Overall, intercropping medicinal and aromatic plants represents a versatile and economically viable approach for sustainable crop production. The selection of compatible species, careful management of planting ratios, and appropriate agronomic practices are critical to maximizing both biological and economic benefits. Such strategies not only increase farm profitability but also promote environmental sustainability and resilience in diverse cropping systems. This review explores the effects of MAP integration on agroecological performance and identifies key mechanisms and practical outcomes.