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Anticancer Activity of Alkynylgold(I) with P(NMe2)(3) Phosphane in Mouse Colon Tumors and Human Colon Carcinoma Caco-2 Cell Line

Publicated to:Inorganic Chemistry. 58 (22): 15536-15551 - 2019-01-01 58(22), doi: 10.1021/acs.inorgchem.9b02528

Affiliations

Inst Invest Sanitaria Aragon IIS Aragon, Zaragoza 50009, Spain - Author
Univ Granada, Fac Quim, Dept Quim Inorgan, Severo Ochoa S-N, E-18071 Granada, Spain - Author
Univ Zaragoza, CITA, IA2, E-50013 Zaragoza, Spain - Author
Univ Zaragoza, Fac Vet, Dept Farmacol & Fisiol, Miguel Servet 177, E-50013 Zaragoza, Spain - Author
Univ Zaragoza, Inst Sintesis Quim & Catalisis Homogenea, CSIC, Plaza S Francisco S-N, E-50009 Zaragoza, Spain - Author
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Abstract

Keywords: Animal; Animals; Antineoplastic agent; Antineoplastic agents; Antitumor-activity; Apoptosis; Binding; Caco-2 cell line; Caco-2 cells; Chemistry; Colon tumor; Colonic neoplasms; Colorimetric assay; Complexes; Coordinated gold compound; Crystallography, x-ray; Dapta ligands; Derivatives; Dna; Drug effect; Female; Human; Humans; In-vitro cytotoxicity; Institute for cancer research mouse; Mice, inbred icr; Models, molecular; Molecular model; Organogold compound; Organogold compounds; Phosphine; Phosphine derivative; Phosphines; Thioredoxin reductase; X ray crystallography

Quality index

WoS Scopus by Scimago
Best Categ.Chemistry, Inorganic & NuclearInorganic Chemistry
WoSScopus by ScimagoSPIFecytAgaurDialnetCircCapesMiar
IF4.8251.349--11.000
Rank4/456/67
QQ1Q1-----A1
DD1D1-
TT1T1
PP92P9
Index ERIC-
Index Emergin-
Index AHCI-