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Determination of total plasma oxysterols by enzymatic hydrolysis, solid phase extraction and liquid chromatography coupled to mass-spectrometry.

Publicado en:Journal Of Pharmaceutical And Biomedical Analysis. 150 396-405 - 2018-02-20 150(), doi: 10.1016/j.jpba.2017.12.033

Mendiara I; Osada J; Martínez-Beamonte R;

Afiliaciones

CIBER de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Spain. - Autor o Coautor
CIBER de Fisiopatología de la Obesidad y Nutrición, Instituto de Salud Carlos III, Spain. Electronic address: Josada@unizar.es. - Autor o Coautor
Departamento de Bioquímica y Biología Molecular y Celular, Facultad de Veterinaria, Instituto de Investigación Sanitaria de Aragón-Universidad de Zaragoza, Spain - Autor o Coautor
Departmento de Química Analítica, Universidad de Zaragoza, Spain - Autor o Coautor
Departmento de Química Analítica, Universidad de Zaragoza, Spain. - Autor o Coautor
Human Molecular Genetics Center and Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. - Autor o Coautor
Instituto Agroalimentario de Aragón, CITA-Universidad de Zaragoza, Spain - Autor o Coautor
Instituto Agroalimentario de Aragón, CITA-Universidad de Zaragoza, Spain. - Autor o Coautor
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Resúmen

Palabras clave: 24 hydroxycholesterol; 24-hydroxycholesterol; 25 hydroxycholesterol; 25-hydroxycholesterol; 26 hydroxycholesterol; 27-hydroxycholesterol; 4 beta hydroxycholesterol; 7 hydroxycholesterol; 7 oxocholesterol; Animal; Animals; Animals, genetically modified; Article; Bacterial enzyme; Bacterial protein; Bacterial proteins; Bile salt-stimulated lipase; Blood; Blood level; Bovine; Calibration; Chemical structure; Chemistry; Cholesterol blood level; Cholesterol esterase; Chromatography, liquid; Comparative study; Cyp7b1 knock-out rat; Cyp7b1 protein, rat; Cytochrome p450 family 7; Deficiency; Enzymatic hydrolysis; Enzymology; Fischer 344 rat; Genetics; Human; Humans; Hydrolysis; Incubation time; Lc–ms; Limit of detection; Liquid chromatography; Liquid chromatography-mass spectrometry; Male; Nonhuman; Oxysterol; Oxysterols; Pancreas; Pathophysiology; Plasma analysis; Priority journal; Pseudomonas; Pseudomonas aeruginosa; Rat; Rats, inbred f344; Reference standards; Reproducibility; Reproducibility of results; Solid phase extraction; Standard; Standards; Steroid hydroxylases; Steroid monooxygenase; Sterol esterase; Surfactant; Tandem mass spectrometry; Transgenic animal; Unclassified drug

Indicios de calidad

WoS Scopus by Scimago
Best Categ.Chemistry, AnalyticalAnalytical Chemistry
WoSScopus by ScimagoSPIFecytAgaurDialnetCircCapesMiar
IF2.9830.786--11.000
Rank24/8428/106
QQ2Q1-----A1
DD3D3-
TT1T1
PP72P27
Index ERIC-
Index Emergin-
Index AHCI-